- IR@KAHER Belagavi
Recent Submissions
ABSTRACT Introduction and background: India stands one of the highest burdens of tuberculosis (TB) cases worldwide. Delays in diagnosis and lack of adherence to anti-TB drug regimens are common challenges observed among TB patients. Identifying these gaps and raising awareness about TB infection are crucial steps toward achieving the goal of a 'Global end TB strategy’ by 2030. Therefore, this study aims to assess and evaluate the clinical pharmacist counselling and improve the medication com...
ABSTRACT Biochemical Changes in Individuals of High BMI with special reference to Medho Sara (Excellence of Adipose Tissue) and Sthaulya (Obesity) Background: Obesity, or Sthaulya, is a major public health issue, especially in India, where the swift epidemiological change has increased obesity-related ailments. Traditional Ayurvedic principles, such as Medho Sara (the superiority of adipose tissue), offer a foundation for comprehending the physiological and pathological conditi...
1.1 ABSTRACT Introduction: Type 2 Diabetes Mellitus (T2DM) is a metabolic condition characterized by insulin resistance and pancreatic β-cell dysfunction caused by uncontrolled hyperglycaemia. There is also a link of inflammation in the pathogenesis of T2DM. T2DM is a growing concern worldwide, having reached epidemic proportions in many developing and most developed countries. According to American Diabetes Association, uncontrolled T2DM is measured as a glycated hemoglobin lev...
ABSTRACT Introduction and background: Topical corticosteroids abuse is quite common with varied presentations, most commonly on face is an increasing problem encountered by dermatologists in India. Lack of public awareness and the ease of obtaining topical corticosteroids without a prescription are important underlying factors. There is a need to take urgent remedial steps and increase awareness about this problem in Community Pharmacist, Health Sciences Student Population and Pat...
ABSTRACT Background: India, often referred to as the diabetic capital of the world, faces limitations in existing oral antidiabetic drug efficacy. Nitrogen and sulphur-containing heterocycles are potential for managing T2DM by targeting specific biological targets. Objectives: The study employed to design, synthesis and characterize novel nitrogen and sulphur-containing heterocycles, and explore their molecular mechanisms for antidiabetic activity.
ABSTRACT Background: Cucumis melo and Cucurbita pepo widely utilized vegetable fruit and traditionally claimed for hepatoprotective activity. However, their hepatoprotective molecular mechanisms are not yet elucidated. The current study utilized multiple in silico approaches to identify the mechanisms of action of bioactive phytocompounds of C. melo and C. pepo and potential targets of liver cirrhosis, validated through cytotoxic and hepatoprotective effect of both the herbs in He...
ABSTRACT Background: Stroke is a major public health problem in India with an increase in the prevalence of post-stroke disabilities. There is a lack of studies on the determinants and consequences of stroke in India. Objective: To study the determinants of post-stroke disabilities and their consequences in terms of caregiver burden, family needs, coping strategies and quality of life.
ABSTRACT Introduction: This study aimed to evaluate the impact of a structured intervention on medication adherence among epilepsy patients. Medication adherence is crucial for managing epilepsy effectively, yet non-compliance remains a significant challenge. The structured intervention included patient counselling, information leaflets, and other support measures to manage adverse effects and improve adherence. The study also aimed to assess the impact of this intervention on qua...
ABSTRACT Background: Menopause is a demanding phase in a woman’s life, often accompanied by a rise in musculoskeletal concerns and obesity, requiring early and effective intervention. The influence of High-Intensity Interval Training (HIIT) and Hatha yoga on musculoskeletal health in postmenopausal women remains inadequately studied. While both exercise methods have distinct characteristics, they also share notable differences and similarities. Aims: To assess and compare the e...
Background: Among vector-borne diseases malaria affects nearly half of the world's population, as estimated by the WHO in 2022, and the disease was responsible for over 249 million people in 85 countries. Another global vector-borne threat is lymphatic filariasis that affects 859 million people in 50 countries, causing long lasting and severe morbidity. However, currently, while antimalarial campaigns are facing the problem of drug resistance, antifilarial programmes are facing the ...
ABSTRACT Background Growth and development are unique features in children. Child grows continuously till the adulthood. There are periods of rapid growth and slower growth in every child but the pattern of growth differs in children depending on various factors ranging from genetics to environment, socio demography. Nutrition plays an important role in maintaining growth of children. Objectives Primary Objective: 1. Assessment of growth velocity among children aged betwee...
ABSTRACT Background Lung cancer is reported very commonly in all the diagnosed human cancer types with the highest death rate. It is treated with surgical resection, radiation, and chemotherapy but it has many adverse effects, toxicity, drug resistance and disease recurrence. Many effective anticancer drugs are used in the treatment but there is a need to improve the therapeutic potential of existing and development of new anticancer drugs. Phytoconstituents are effective and ha...
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