http://localhost:8080/xmlui/handle/123456789/57 2026-01-20T10:21:38Z http://localhost:8080/xmlui/handle/123456789/1994 Title: Assess and compare the changes in periodontal soft and hard tissue in maxillary and mandibular anterior teeth before and after orthodontic treatment: a retrospective study Authors: REG.NO:IK0222005 Abstract: INTRODUCTION Orthodontic tooth movement has an effect on periodontal soft and hard tissue. When forces are applied to teeth, pressure and compression zones are formed in the periodontal ligament which leads to remodeling of the periodontal structures. Periodontal parameters such as keratinized tissue width, crestal bone level and clinical crown height helps to determine this effect of orthodontic forces on periodontal health. These parameters are not routinely examined before and after orthodontic treatment, therefore patient’s record can be used to obtain the required data. Therefore, this study was designed to Assess and compare the changes in periodontal soft and hard tissue in maxillary and mandibular anterior teeth before and after orthodontic treatment retrospectively. AIM Assess and compare the changes in periodontal soft and hard tissue in maxillary and mandibular anterior teeth before and after orthodontic treatment. 2025-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/1993 Title: Estimation of salivary matrix metalloproteinases- 8 (mmp-8) and its correlation to periodontal inflamed surface area (pisa) before and after non-surgical periodontal therapy Authors: REG.NO:IK0222004 Abstract: INTRODUCTION Matrix metalloproteinase-8 (MMP-8) is a key enzyme involved in collagen degradation and is considered a promising indicator of periodontal tissue destruction. Given its involvement in periodontal inflammation, MMP-8 holds promise as a biomarker for identifying individuals at risk of developing periodontitis. MMP-8 is detectable in oral fluids such as saliva and gingival crevicular fluid. The available studies used conventional periodontal parameters which inadequately measured the inflammatory burden posed by the periodontal disease. A new tool Periodontal Inflamed Surface Area (PISA) was developed which provides a quantitative measure of inflammation by calculating the surface area of bleeding pocket epithelium using CAL, recession and bleeding on probing. No existing studies have explored the relationship between MMP-8 and PISA levels pre and post non-surgical periodontal therapy. AIM Estimation of salivary MMP-8 and its correlation to PISA before and after non-surgical periodontal therapy 2025-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/1992 Title: Comparative efficacy of mucoadhesive film containing silver nano particles and mucoadhesive film containing curcumin on wound healing after periodontal surgery – a randomized controlled trial Authors: REG.NO:IK0222003 Abstract: INTRODUCTION The periodontium supports and preserves teeth, but periodontitis, which affects up to half of the global population, undermines these structures. Periodontal dressings (pack) are protective materials applied over the wound created by periodontal surgical procedures. The main objectives of periodontal dressings are to obtain an optimized healing and ensure minimum discomfort to the patient along with wound protection. While periodontal dressings aid in healing, they may also encourage bacterial growth. To address this, drug-loaded dressings including substances such as silver nanoparticles and curcumin have been investigated for antibacterial and anti-inflammatory activities. Given the potential of mucoadhesive films for targeted administration, this study assesses and compares the wound-healing efficacy of curcumin- and silver nanoparticle-based films after periodontal surgery. AIM To assess and juxtapose the impact of mucoadhesive films containing silver nano particles and mucoadhesive films containing curcumin on wound healing after periodontal surgery. 2025-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/1991 Title: Comparative evaluation of antimicrobial effect of indocyanine green and methylene blue dye as photosensitizers for photodynamic therapy as an adjunct to scaling and root planing in patients with moderate periodontitis - a randomized controlled trial Authors: REG.NO:IK0222002 Abstract: INTRODUCTION In recent years, photodynamic therapy (PDT) with the help of lasers has been used to decontaminate the pocket environment as it is a minimally invasive treatment that activates the immune system, has low systemic toxicity, and possesses high bactericidal properties. Combining lasers and photosensitizing agents can result in photo destruction of target cells due to cytotoxic effect in the presence of oxygen. The photokilling rate is highly related to interaction of reactive oxygen species produced, ability of photosensitizers in incorporating into microorganisms and light devices/microorganism type. While methylene blue (MB) and indocyanine green (ICG) are present in the dental practice as photosensitizers there is an acute paucity of literature comparing their efficacy in terms of improvement of clinical parameters and suppression of periodontal pathogens. AIM To assess and compare the antimicrobial effects of indocyanine green and methylene blue dye as photosensitizers for photodynamic therapy as an adjunct to scaling and root planing in patients with moderate periodontitis 2025-01-01T00:00:00Z