http://localhost:8080/xmlui/handle/123456789/68 2026-01-21T14:24:29Z http://localhost:8080/xmlui/handle/123456789/1805 Title: Detection of mycobacterium tuberculosis by polymerase chain reaction – a one year cross - sectional study in the rural population of belagavi district. Authors: REG NO: BIO121002 Abstract: ABSTRACT STUDY BACKGROUND: Tuberculosis (TB) has long been a significant threat to humanity, affecting health, society, and the economy. Recently, the Belagavi district experienced a decline in TB notifications amid the COVID-19 pandemic, potentially leading to increased morbidity, mortality, and household transmission. OBJECTIVES: The main objectives of this discourse were to detect Mycobacterium tuberculosis in suspected Pulmonary tuberculosis patients using conventional PCR on sputum samples and to examine the demographic profile of TB patients attending hospitals in and around Belagavi. 2024-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/1804 Title: Identification of opportunistic Infections caused by intestinal Parasites in immunocompromised Patients Authors: REG NO: BI0121001 Abstract: Introduction: Parasitic diseases remain a significant cause of morbidity and mortality worldwide. Conditions such as HIV/AIDS, the use of immunosuppressive medications, blood cancers, and other chronic illnesses increase patients' vulnerability to opportunistic infections. In a rising number of immunocompromised individuals, including transplant recipients and those undergoing immunosuppressive therapies, chronic diarrhoea is becoming more prevalent. Emerging pathogens such as Coccidia and Microsporidia play a crucial role in exacerbating this problem. This study aimed to investigate opportunistic intestinal parasites in immunocompromised patients. Objectives: 1. To identify various Parasitic Opportunistic Infections (OIs) in immunocompromised patients/HIV patients. 2. To co-relate the OI with patient’s clinical manifestations. 3. To co-relate OIs with other laboratory parameters of the patients (complete blood picture), CD4 count, Erythrocytic Sedimentation rate (ESR), CD4 count, C-Reactive protein, D-dimer, and radiological investigations etc). 2024-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/1429 Title: prevalence of candidemia in high-risk neonates of neonatal intensive care unit -a one-year cross sectional study. Authors: REG. NO. BIO120002 Abstract: Background: Fungal sepsis in neonates is on rise among blood stream infection, it is the third most common etiological agent for sepsis and the changing epidemiology to non-albicans Candida is grossly evident. Fungal isolates are showing azole resistance which were the most common prophylactic treatment used, now made treatment choices difficult for neonate ICU clinicians. Newer class of antifungal drugs especially Echinocandins (Caspofungin) came into real time practice in azole resistant Candida causing sepsis. Objective: 1. To study the prevalence of Candidemia in high-risk neonates of NICU 2. To study Caspofungin (Echinocandin) antifungal susceptibility in Fluconazole resistant Candida isolates by E test / MIC test strip method. 2023-06-15T00:00:00Z http://localhost:8080/xmlui/handle/123456789/1428 Title: Phenotypic detection of selected Virulence factors of candida species Isolated from women of reproductive Age with vulvovaginal candidiasis Authors: REG. NO. BIO120001 Abstract: Background: Overgrowth of Candida species in the female lower genital tract, the vulva & the vagina results in vulvovaginal candidiasis (VVC). Production of virulence factors like biofilm & various enzymes (hemolysin, phospholipase, esterase) contributes towards its pathogenicity. Hence, in view of these factors contributing to pathogenic nature of the species & emerging resistance to antifungals; the study was taken aiming to detect the virulence factors of Candida species isolated from women of reproductive age group. Objectives: 1. Phenotypic detection of selected virulence factors (Biofilm production, Hemolytic activity, Phospholipase activity, Esterase activity) of Candida species isolated from women of reproductive age with Vulvo-vaginal Candidiasis. 2.To detect the anti-fungal resistance of the isolates. 2023-06-15T00:00:00Z