http://localhost:8080/xmlui/handle/123456789/1044 Wed, 14 Jan 2026 20:15:36 GMT 2026-01-14T20:15:36Z http://localhost:8080/xmlui/handle/123456789/2027 Title: Study Of Magnetic And Transport Anomalies In Rare Earth Based Intermetallics And Oxides Authors: Iyer Karthik Krishnan Abstract: Abstract There has been a considerable interest in understanding the physical properties of the compounds containing rare-earths, not only from the angle of basic science but also considering growing application potential. Current trends in condensed matter area suggest that investigation of new materials in particular are important in this respect, as such studies often paved the way for new concepts and resultant applications. Keeping this in mind, some ternary compounds – less investigated in the literature – have been taken up for magnetic investigations, and also for exploring antibacterial studies. Such compounds for our studies are: Nd2RhSi3, Er2RhSi3, Ho4PtAl, Er4PtAl, and Dy4RhAl among metals and spin-chain insulators Tb2BaNiO5 and Tb2BaCoO5, in both bulk and nanoforms. There are structural features facilitating ‘geometrically frustrated magnetism’ – a current trend in magnetism - in the above-mentioned metallic compounds. While many novel features (revealing structure-property relation) in the magnetic behavior of these compounds are reported in this thesis, main highlights are: (i) Establishment of an exceptional magnetism of Nd2RhSi3. (ii) Establishment of antiferromagnetism at 5 K in Er2RhSi3, however, with concurrent cluster spin-glass features, attributable to partially disordered antiferromagnetism; 1/3 magnetization plateau – less known among metals – and corresponding magnetoresistance plateau are intriguing findings. (iii) Ho4PtAl and Er4PtAl exhibit a re-entrant cluster spin-glass behavior, with the onset of an antiferromagnetic ordering; isothermal entropy change is very large at the onset of magnetic order, making these compounds useful for magnetic refrigeration applications. Dy4RhAl exhibits spin-glass features which coexists with xxvii antiferromagnetic order (18 K); this magnetic behavior is interestingly different from that of Dy4PtAl, which is ferromagnetic. (iv) Pressure studies on the magnetic ordering temperatures of well-known ‘exotic’ multiferroic systems. Tb2BaNiO5 and Tb2BaCoO5 bring out how magnetism of localized 4f electrons behave in a complex fashion to the application of external and chemical pressures, influencing other coupled phenomena. (v) A reduction in particle to nanoform in Dy4RhAl, leads to the evolution of a Griffiths-phase like behavior (a novel concept in magnetism), suppressing antiferromagnetic order – a rare demonstration in magnetic metals. In other cases, the changes in magnetic properties in nanoform are subtle. This reinforces the fact that one needs to be cautious while employing nanoparticles for medicinal applications based on the properties of the bulk forms, though none of these compounds are efficacious in inhibition of bacterial and fungal growths. The studies serve as a classic study for exploration of such rare-earth intermetallic materials for medicinal applications. Mon, 01 Jan 2024 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/2027 2024-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/1684 Title: Assessment of Genetic and Phytochemical Variations of Leptadenia reticulata from Different Geographical Regions of India Authors: Mr.Roshan Kumar Sharma Abstract: Leptadenia reticulata (Retz.) Wight & Arn, a highly valued and extensively traded medicinal plant, plays a crucial role in Ayurvedic practices, primarily for its revitalizing, rejuvenating, and lactogenic properties. However, because of the established medicinal properties and increase in demand across the world, the plants are being overexploited and are rapidly decreasing in number. It is therefore important to carry out population genetic studies on the plant to understand the existing variations in their gene pool and their correlation with respective phytoconstituents so that appropriate conservation strategies can be planned. Depleting numbers, and inadvertent mistakes in identification coupled with rampant substitution and adulteration has necessitated the development of better tools for correct identification and differentiation of this medicinally important plant from common adulterants/substitutes. Objectives: (i) To study the DNA profile of Leptadenia reticulata, from different geographical regions of India using ISSR/RAPD primers. (ii) To investigate the phytoconstituent variation in Leptadenia reticulata using the fingerprinting method. (iii) To develop the molecular markers for identification and differentiation of Leptadenia reticulata from its adulterants and substituents. Mon, 01 Jan 2024 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/1684 2024-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/1681 Title: Statistical model in Estimation and Monitoring of Covid 19 Authors: Mr.Noel George Abstract: Background: In the last two decades, the world has seen several viral outbreaks, notably the H1N1 in 2009 and Nipah virus in 2018. The COVID-19 pandemic, declared by WHO in early 2020, presented unprecedented challenges due to its high contagion and potential for asymptomatic spread. Early data often underestimated the pandemic's extent, emphasizing the need for comprehensive health crisis management. Statistical models have been crucial in understanding and responding to COVID-19, from tracing its origins in Wuhan, China, to its global spread. These models have informed public health strategies, adapting to regional differences in the pandemic's impact. The significance of this study lies in using statistical models to estimate and monitor COVID-19, aiding policymakers and healthcare professionals. It sheds light on the virus's transmission and future trends, guiding targeted actions and preparedness for future pandemics. The research underscores the importance of current data over historical records, considering behavioural changes, new virus strains, and varying testing/reporting methods. Objectives: The objectives of this study are to establish a model for the COVID-19 pandemic and provide effective methods, enabling planners and healthcare providers to take appropriate actions for the management, containment, and control of the pandemic. Mon, 01 Jan 2024 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/1681 2024-01-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/1675 Title: Augmentation of cisplatin with thymoquinone to target chemoresistant ovarian cancer in vitro study Authors: Ms.Shivani Shirish Tendulkar Abstract: Background: Ovarian cancer (OvCa) is the leading gynecological cancer and has been reported to have multi-drug resistance. Due to poor prognosis, women have low survival rates and therapies have negative impacts on the quality of life. Resistance to conventional treatments such as chemotherapy and radiation therapy is the reason for the need for innovative therapies. Phytochemicals (PCs) have demonstrated significant potential in the field of OvCa by inhibiting metastasis of cancer cells. Thymoquinone (TQ) is a promising drug in the field of OvCa for inhibiting the cell proliferation of cancer cells. Objectives: The study demonstrates cisplatin (CDDP)- induced chemoresistance in OvCa using in-vitro assays. The study also determines the anti-chemoresistance mechanisms of CDDP along with TQ in OvCa. Mon, 01 Jan 2024 00:00:00 GMT http://localhost:8080/xmlui/handle/123456789/1675 2024-01-01T00:00:00Z