Solubility Enhancement, System  design for transbuccal delivery, in-vitro characterization and in-vivo evaluation of  Lovastatin

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DC Field	Value	Language
dc.contributor.author	Mrs.Bhuvaneshwari R.SharannavarM	-
dc.date.accessioned	2022-02-16T07:57:00Z	-
dc.date.available	2022-02-16T07:57:00Z	-
dc.date.issued	2020	-
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/1140	-
dc.description.abstract	Abstract: Background: Lovastatin (LVS); HMG CoA inhibitor, is a drug of choice for hyperlipidemia. Its clinical efficacy is limited due to its low aqueous solubility, incomplete absorption, short-half life, first pass metabolism, low bioavailability, and adverse effects etc. Objective: The objective of the present study was to improve the solubility of Lovastatin and develop mucoadhesive film of solid dispersions for buccal delivery to enhance bioavailability.	en_US
dc.language.iso	en	en_US
dc.publisher	KLE Academy of Higher Education and Research, Belagavi	en_US
dc.subject	Lovastatin, PEG 4000, PVPK30, Solid dispersion, HPMCK4M, HPMC E5LV, chitosan, Ex-vivo bioadhesion, ex-vivo permeation, bioavailability.	en_US
dc.title	Solubility Enhancement, System design for transbuccal delivery, in-vitro characterization and in-vivo evaluation of Lovastatin	en_US
dc.type	Phd Thesis	en_US
Appears in Collections:	Faculty of Pharmacy

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