To assess and compare the Antimicrobial activity of licorice gel And chlorhexidine gel on porphyromonas Gingivalis, aggregatibacter Actinomycetamcomitans and tannerella Forsythia - an in-vitro study

Abstract

ABSTRACT INTRODUCTION: Periodontitis is an oral disease that is known to cause inflammation of tooth supporting structures due to presence of plaque (dental biofilm). It results in progressive breakdown of the periodontal ligament and its supporting tissues. It is caused by the accumulation of dental plaque which is a structurally and functionally well-organized biofilm that normally maintains a homeostatic relationship with the human host. A disturbance in this balance causes a microbial shift from commensal to pathogenic periodontal pathogens that mark the beginning of periodontal disease. The frontline treatment for periodontitis includes scaling and root planning (SRP) that effectively removes the plaque and restores the periodontium to a healthy state and antimicrobial agents such as Chlorhexidine that are often used as an adjunct to SRP to aid and maintain the healthy state of tissues. However these antimicrobial agents have side effects such as alteration of taste, discoloration of teeth and development of antimicrobial resistance. Hence, there has been a shift in research towards discovering, isolating and developing natural herbal plant extracts as effective antimicrobial agents. The purpose of the current study is to assess and compare the antimicrobial activity of the one such herbal plant extract Glycyrrhiza glabra (licorice) gel and chlorhexidine gel on Porphyromonas gingivalis, Aggregatibacter actinomycetamcomitans and Tannerella forsythia. AIM: To assess and compare the antimicrobial activity of the licorice gel and chlorhexidine gel on Porphyromonas gingivalis, Aggregatibacter actinomycetamcomitans and Tannerella forsythia.