To assess and compare the Antimicrobial activity of psoralea Corylifolia gel and chlorhexidine gel Against porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans – an in-vitro study

Abstract

ABSTRACT INTRODUCTION: Periodontitis is a complex infectious disease with several etiologic and contributory factors. The disease process has a mainly bacterial origin were primary colonizers in turn cause an environment which is favorable for development secondary colonizers like Porphyomonas gingivalis (PG) and Aggregatibacter actinomycetemcomitans. These organisms are an intrinsic part of the dental biofilm and are known to be adherent to it. They also have the capacity to invade tissues locally. These characteristics of the bacteria play an important role in the pathogenesis of the disease. Scaling and root planing (SRP) is the first step and an essential phase of periodontal treatment, but it alone cannot eliminate tissue invading pathogens which suggest the need for adjuvant antimicrobial therapy. Chlorhexidine is considered the gold standard in antimicrobial agents used for treatment of periodontitis but it has side effects like bitter taste, staining of teeth and tongue, increased supragingival calculus formation and parotid swelling. This has led to increase in the demand for herbal medicine as they show fewer side effects and they make low cost drugs. The purpose of the study was to assess and compare the antimicrobial activity of Psoralea Ccorylifolia gel and chlorhexidine gel against Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans. AIM: To assess and compare the antimicrobial activity of Psoralea corylifolia gel and chlorhexidine gel against Porphyromonas gingivalis and Aggregatibacter actinomycetaemcomitans.