Evaluation and comparison of efficacy of Polyherbal gel containing ashwagandha And ginger as an adjunct to scaling and Root planing in chronic periodontitis – an In-vivo study

Abstract

ABSTRACT Background: Periodontitis is a multifactorial, infectious chronic inflammatory disease of periodontium having the ability to initiate immune response causing periodontal destruction eventually leading to bone loss. The primary goal of periodontal therapy is to reduce microbial load using various non-surgical approaches mainly through scaling and root planing which is considered as a gold standard. It fails to eliminate the pathogenic bacteria completely especially at the base of the periodontal pocket and the areas inaccessible to periodontal instruments. Therefore, the use of local drug delivery in the affected area using synthetic antimicrobials was introduced as an adjunct to scaling and root planing. To overcome the side-effects of these synthetic drugs, plant-based medicinal substitutes were incorporated alone or in combination in the treatment of chronic periodontitis. Aim: To evaluate and compare the efficacy of a polyherbal gel containing Ashwagandha and Ginger as a Local Drug Delivery Agent as an adjunct to scaling and root planing, on the clinical and biochemical parameters in patients with chronic periodontitis.