Comparison of platelet rich plasma injection with Normal saline dressing in rate of chronic ulcer Healing, a one year randomised control trial

Abstract

INTRODUCTION Chronic wounds are critical health challenge in India. Our goal is to establish fixed protocols to simplify wound healing. Chronic wound are those which donot heal within a time period of 3 months. Various different treatment strategies are available for promoting wound healing but no specific protocols are present for the same. Platelet rich plasma is one of the upcoming treatment modality available for chronic wound healing. PRP acts by releasing various growth factors such as platelet derived growth factor, fibroblast growth factor, Epidermal Growth Factor (EGF), platelet derived angiogenesis factor and platelet factor-4. These factors are released in the local wound environment which leads to increase wound healing. Chronic wound has a great financial burden and mental burden over the patient. So proper wound care should be given and usage of platelet rich plasma can enhance wound healing. AIM To compare injection platelet rich plasma dressing versus normal saline dressing in healing of chronic ulcers in terms of mean percentage reduction in ulcer area.