Comparison of low dose intravenous ketamine infusion versus Placebo for postoperative analgesia following laparoscopic Appendicectomy under general anaesthesia: one year hospital Based double blind randomised clinical trial

Abstract

BACKGROUND: In recent times laparoscopic appendicectomy is preferred more than open appendicectomy to decrease postoperative pain and length of hospital stay. However, the surgery is not always pain free. Several methods have been used to treat postoperative pain effectively following laparoscopic appendicectomy. Recent interest has been focused on the administration of N-methyl-D-aspartate receptor antagonists for the treatment of postoperative pain, of which Ketamine is an essential drug. OBJECTIVE: To evaluate the efficacy of low dose intravenous Ketamine infusion for acute postoperative pain management for laparoscopic appendicectomy.