Effect on kidney function of intravenous Contrast-enhanced ct using iso-osmolar and lowosmolar Iodinated Contrast Medium

Abstract

Introduction: Iodinated contrast media (CM) are well tolerated, and their use is on the rise. The most life-threatening side effect of CM is acute renal damage. This study aimed to find the incidence of CI-AKI using iso-osmolar (IOCM) and low-osmolar contrast media (LOCM) in the general population. Material and methods: This was hospital-based observational research with participants above the age of 18. An early increase in serum creatinine (SCr) concentration of at least 0.5 mg/dl or a 25% increase in creatinine from baseline were categorized as CI-AKI. The major outcome variable was serum creatinine levels. The key explanatory variable was the IV contrast agent. For quantitative variables, mean and standard deviation were used, whereas, for categorical variables, frequency and proportion were used.