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http://localhost:8080/xmlui/handle/123456789/1245| Title: | An in vivo and In vitro study of hepatocellular Carcinoma complications in diabetes mellitus |
| Authors: | Mr.Bhrigu Kumar Das |
| Keywords: | Diabetes mellitus, Hepatocellular carcinoma, Streptozotocin, Diethylnitrosamine, Asarone, Metformin HCl, HepG2 cells. |
| Issue Date: | 2022 |
| Publisher: | KLE Academy of Higher Education and Research, Belagavi |
| Abstract: | Objectives: This study aims to develop an animal model to replicate the clinical evidence for diabetic-HCC conditions and to evaluate the beneficial effects of asarone and metformin HCl in controlling the progression of HCC. The objectives of the present study are: 1. To investigate the role of hyperglycemia in aiding the progression of hepatocellular carcinoma. 2. To evaluate the role of asarone and metformin HCl in controlling the progression of hepatocellular carcinoma during hyperglycemia, and understand the underlying molecular mechanism. |
| URI: | http://localhost:8080/xmlui/handle/123456789/1245 |
| Appears in Collections: | Faculty of Pharmacy |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Thesis_Bhrigu Kumar Das_Part1.pdf | 21.61 MB | Adobe PDF | View/Open | |
| Thesis_Bhrigu Kumar Das_Part2.pdf | 19.05 MB | Adobe PDF | View/Open |
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