Evaluation of expression of immunohistochemical markers high molecular weight cytokeratin (hmwck) and alpha-methylacyl coa racemose (amacr) in prostatic needle biopsies and transurethral resection of prostate (turp) specimen – a one year observational study

Abstract

BACKGOUND and OBJECTIVES: In view of increasing incidence of Prostate cancer with age, its early detection and management is of utmost importance. Digital rectal examination, clinical picture and USG findings are non-specific. This study was conducted to resolve the problems a pathologist face in diagnosing cases of prostatic lesions having a suspicious morphology. IHC staining (HMWCK and AMACR) was done to distinguish benign from malignant lesions