Hyperuricemia As An Early Marker In Predicting Mortality And Morbidity In Patients With Sepsis

Abstract

Background and Objectives Sepsis continues to be a medical and financial burden for both developed and developing countries, and affects all age groups. The normal value of uric acid varies with age, gender, ethnicity and physiologic status of the population. Uric acid levels in septicemic patients and their correlation with increased global prevalence along with septic shock depends on its severity. The use of uric acid levels for grading the severity and its outcome in these patients is widely advocated despite caveats to its use with septicemia and conditions like shock being cited as a major confounding factor. The value of serum uric acid may be erroneous in those with septicemia and its sequelae, thus mandating its evaluation. The objective of this study was to identify a correlation between severity of sepsis & outcome of patients and the derangement of uric acid levels in an adult population.