Effect of benzydamine hydrochloride [0.15%] spray And lidocaine hydrochloride [10%] spray on Endotracheal tube cuff in reducing postoperative Sore throat, hoarseness of voice, and cough –a randomised clinical trial

Abstract

INTRODUCTION: Endotracheal intubation is a gold standard procedure followed in airway management to secure and maintain a definitive airway in patients undergoing surgery under general anesthesia. Postoperative sore throat [POST] is a common adverse event after general anesthesia with an incidence varying from 40% to 99%. Sore throat comprises symptoms of laryngitis, tracheitis, hoarseness, and cough. The symptoms are a result of mucosal injury with resulting inflammation caused by the process of airway instrumentation [i.e., laryngoscopy and suctioning] or the irritating effects of a foreign object [i.e., endotracheal tube]. AIM: To compare the effectiveness of 0.15% benzydamine hydrochloride puffs at the cuff level of the endotracheal tube with that of 10% lidocaine hydrochloride puffs in reducing the incidence and severity of postoperative sore throat, hoarseness of voice, and cough in patients undergoing general anesthesia with endotracheal intubation