Phenotypic detection of selected Virulence factors of candida species Isolated from women of reproductive Age with vulvovaginal candidiasis

Abstract

Background: Overgrowth of Candida species in the female lower genital tract, the vulva & the vagina results in vulvovaginal candidiasis (VVC). Production of virulence factors like biofilm & various enzymes (hemolysin, phospholipase, esterase) contributes towards its pathogenicity. Hence, in view of these factors contributing to pathogenic nature of the species & emerging resistance to antifungals; the study was taken aiming to detect the virulence factors of Candida species isolated from women of reproductive age group. Objectives: 1. Phenotypic detection of selected virulence factors (Biofilm production, Hemolytic activity, Phospholipase activity, Esterase activity) of Candida species isolated from women of reproductive age with Vulvo-vaginal Candidiasis. 2.To detect the anti-fungal resistance of the isolates.