Evaluation of efficacy of transdermal Ketoprofen patch in comparison to Transdermal diclofenac patch as an Analgesic in patients undergoing Orthodontic extractions – a randomised Split mouth study

Abstract

Introduction: NSAIDs till day are the most prescribed analgesics for the control of post-exodontia pain and can be administered by oral, parenteral, transdermal routes etc. Transdermal patches possess the advantages of providing sustained release of the drug, are non-invasive, bypass first pass metabolism and eliminate gastrointestinal adverse effects. In this study, the efficacy of single application of Diclofenac 200 mg transdermal patch and Ketoprofen 30 mg transdermal patch for post orthodontic exodontia pain relief over 24 hours post operatively was compared.