Processing of hydrated amnion chorion Membrane from placenta and comparing with Dehydrated amnion chorion membrane for the Proliferation of periodontal ligament Fibroblast activity– an in-vitro study.

Abstract

Background: Periodontitis is a multifactorial chronic inflammatory disease of periodontium leading to periodontal destruction eventually leading to bone loss. The primary goal of periodontal therapy is to restore the supporting tissues and prevent further attachment loss. Factors such as appropriate cells, signals, scaffolds are required for the successful outcome of periodontal regeneration. Different methods have been used in the past along with incorporation of biomaterials like derivatives and placental membranes for periodontal regeneration that will provide favourable wound healing. Aim: To process and assess the efficacy of Hydrated amnion chorion membrane (HACM) and Dehydrated amnion chorion membrane (dHACM) on proliferation of Periodontal ligament fibroblast cells.