Investigation of Anti obesity Potential of Heartwood Hydroalcoholic Extract of Acacia suma Roxb in High Fat Diet Fed C57BL 6 Mice

Abstract

Background: Obesity is defined as “Chronic complex diseases characterize with excessive adiposity that impairs health. BMI is a major indicator of obesity measured as weight in kilogram divided by height in meter-square. Other than obesity metabolic syndrome includes glucose intolerance, insulin resistance, lipid disturbance, hypertension and cardiac diseases. Aim and objectives: The study aimed to investigate the anti-obesity effect of Acacia suma (Roxb.) in the experimental animal model. The objectives of this study are to predict the binding affinity of phytoconstituents from Acacia suma using in-silico approach and investigation of anti-obesity activity of heartwood hydroalcoholic extract of Acacia suma using 3T3-L1 cell line and in experimental animal model.