EFFECT OF GINGKO BILOBA VERSUS CAROVERINE IN THE TREATMENT OF TINNITUS- A ONE YEAR RANDOMIZED CONTROL STUDY’

Abstract

Introduction: Chronic tinnitus is a prevalent condition that causes distress to at least 10-15% of the adult population which directly affects the quality of life and is commonly associated with anxiety and depression. Gingko biloba, a well-known herbal medicine exhibits anti-inflammatory, anti-oxidant, and free radical scavenging, cerebral glucose consumption, platelet aggregation inhibition, neurotransmitter modulation, and vasomotor activity. It enhances microcirculatory flow, which in turn increases blood fluidity. Caroverine is a glutamate receptor antagonist and also reduces the excitability of the nerve cell function.it is postulated that caroverine blocks both NMDA and AMPA induced firing. Objective: To study the effect of caroverine versus gingko biloba in the treatment of tinnitus patients.