ROLE OF VITAMIN D SUPPLEMENTATION IN ADDITION TO BETAHISTINE AS COMPARED TO BETAHISTINE ALONE IN PATIENTS OF BENIGN PAROXSYMAL POSITIONAL VERTIGO: A ONE YEAR RANDOMIZED CONTROLLED STUDY IN KLES Dr PRABHAKAR KORE HOSPITAL

Abstract

BACKGROUND: BPPV is defined as a unilaterally predominating vestibular impairment of peripheral origin. It is marked by episodes of vertigo. In clinical practice, it is the most frequently occurring peripheral vestibular disease and ranks the top most among otolaryngology variety of vertigo 1 . Otoconia are in a dynamic state whose mineralization and turnover depend on calcium. Vitamin D is essential for calcium metabolism and may have an impact on the density and matrix of CaCO3 crystals . The generation of otoconial particles in the vestibular system and the method by which Ca2+ & P are deposited in bone and teeth are all directly impacted by vitamin D 11 . On the Ca2+ channel transport system of the labyrinth, vitamin D receptors can be seen, and they regulate the proper calcium balance. Deficiency of vitamin D leads to cochlear demineralization and cochlear 12 deafness Severe BPPV is prevalent in vitamin D deficient patients, as this deficiency is linked to developmental progression or severity of several skeletal or non-skeletal 17 conditions. OBJECTIVE :To study the effect of Vitamin D supplementation along with Betahistine as compared to Betahistine alone in treatment of patients of BPPV.