Evaluating anti cholera toxin Activity of pure herbal compounds From traditional medicinal plants

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DC Field	Value	Language
dc.contributor.author	Mrs.Rajitha Charla	-
dc.date.accessioned	2024-08-09T12:42:46Z	-
dc.date.available	2024-08-09T12:42:46Z	-
dc.date.issued	2024	-
dc.identifier.uri	http://localhost:8080/xmlui/handle/123456789/1668	-
dc.description.abstract	Background: Careya arborea, Punica granatum, Psidium guajava, Holarrhena antidysenterica, Aegle marmelos and Piper longum are traditional medicines used to treat diarrheal diseases in India and supported by scientific literature. But their specific activity against Cholera toxin (CT) has not been explored yet. Aim and objectives: The current study aimed to investigate the inhibitory activity of these plants against CT-induced cytotoxicity and enterotoxicity. Polyphenols were selected from plants that showed efficient neutralization activity against CT. The inhibitory activity of selected polyphenols against CTB binding to GM1 receptor was further investigated using computational and experimental approaches.	en_US
dc.language.iso	en_US	en_US
dc.publisher	KLE Academy of Higher Education and Research, Belagavi	en_US
dc.subject	Cholera toxin; Cell free culture filtrate; GM1 ELISA; Cytotoxicity; Docking; Molecular dynamics simulation	en_US
dc.title	Evaluating anti cholera toxin Activity of pure herbal compounds From traditional medicinal plants	en_US
dc.type	Phd Thesis	en_US
Appears in Collections:	Faculty of Interdisciplinary Studies

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