Study of effect of nebulised dexmedetomidine on The onset and duration of spinal anaesthesia, a one Year, hospital-based, randomised clinical trial.

Abstract

Background Spinal anaesthesia is widely used for procedures below the umbilicus. Adjuvants like dexmedetomidine enhance its duration and quality by providing better pain relief and reducing local anaesthetic doses, though they have side effects. Dexmedetomidine, a potent alpha-2 adrenoceptor agonist, is gaining popularity due to its sedative, analgesic, and anxiolytic properties. This study examines the effect of nebulized dexmedetomidine on the onset and duration of spinal anaesthesia. Aims and Objectives To study the effect of nebulized dexmedetomidine on onset and duration of sensory and motor block in spinal anaesthesia. Also, to note the time to first rescue analgesia, and total analgesic requirement in the first twenty four hours postoperatively. To study the level of sedation after administration of the drug and to study side effects of the drug, if any.