Randomised clinical trial to assess the Effect of pre operative topical tranexamic Acid on intraoperative bleeding for quality Of surgical field during fess in patients with Chronic rhinosinusitis

Abstract

Objective: To assess the effect of pre operative local application of TXA by grading the quality of Surgical Field at 15, 30 , and 45 min after the start of surgery using Boezaart Grading. Methods: A hospital based one year randomized clinical trial with a sample size of 70 patients. Depending on the group assigned, nasal cavity was packed 10 mins prior to start of surgery with pledgets soaked in Tranexamic acid in intervention group and xylometazoline soaked pledgets in the control group and the operating surgeon was assessed the surgical field at 15/30/45 mins from start of surgery and to assess the effect of local application of TXA on duration of surgery