Serum Magnesium Level And Its Correlation With Primary Hypertension - One Year Cross Sectional Study

Abstract

ackground and objectives The etiology of primary hypertension are multifactorial, magnesium status in human body is thought to be a crucial factor in pathogenesis of primary hypertension This study was aimed at finding the association between the serum magnesium level and blood pressure in patients with primary hypertension. Methodology The present one year hospital based cross-sectional study was done on 100 patients with primary hypertension from January 2018 to December 2018 in Department of Medicine, KLES Dr Prabhakar Kore Hospital and Medical Research Centre, Belagavi. Results In the present study, 61.00% of the patients were males while 39.00% of the patients were females. The male to female ratio was 1.6:1. Youngest participant in the study was 30 years of age and oldest was 91years. The mean age was 59.30 years with SD + 14.79. out of 100 cases ,11% of patients had serum magnesium less than 1.6mg/dl , 82% of patients had serum magnesium between 1.6 mg/dl to 2.5mg/dl,7 % of patient had magnesium above 2.5 mg/dl. The patients were divided into grade 1 and grade2, where grade 1 patients had systolic BP from 140 to 159 or diastolic 90 to 99 & grade 2 patients had systolic BP more than or equal to 160 or diastolic BP more than or equal to 100 mmHg. The mean serum magnesium level in the study population was 1.99 mg/dl. The mean serum magnesium levels in subjects with grade 1 hypertension was 2.1mg/dl compared to mean value of 1.87 mg/dl in grade 2 hypertension. Comparison between serum magnesium levels and blood pressure revealed statistically significant association with a p-value of 0.0073. study showed inverse association of serum magnesium levels with both systolic and diastolic blood pressure recordings. Conclusion and interpretation The present study showed a significant inverse association between serum magnesium level and blood pressure in patients with primary hypertension.