Inj.Oxytocin 10IU IM Vs Inj. Oxytocin 5IU IM + Inj.Methyl Ergometrine 0.2mg IM Vs Inj.Carbetocin 100mcg IM during AMTSL In vaginal Deliveries – A Randomized Controlled Trial

Abstract

Background – Obstetric haemorrhage is one of the leading cause of (mainly (PPH) Post Partum Hemorrhage) of maternal mortality, accounting for 35% of maternal deaths worldwide (WHO). In order to achieve SDG goal of 70 prevention of PPH is essential. Inj Syntometrine (Inj Oxytocin 5IU + Inj Methyl ergometrine 0.5mg) is superior to other uterotonics, with significant side effects mainly due to the higher dose of Inj Methyl Ergometrine. The current study is undertaken with same combination as in Syntometrine but with a lower dose of Inj.Methyl ergometrine of 0.2mg to find out the effectiveness with other uterotonics (Inj.Oxytocin 10IU and Inj.Carbetocin 100mcg). Aims and Objectives – Primary objective - To compare the effectiveness of the 3 uterotonics which helps in reducing post-partum blood loss. Secondary objective – To assess the requirement of additional uterotonics in management of post-partum bleeding.