study of ki67 expression in oral and oropharyngeal squamous cell carcinoma

Abstract

Introduction: Oral and oropharyngeal squamous cell carcinomas are a common cancers in India, particularly in males, and are a significant cause of death. The major risk factors include tobacco and alcohol. Ki67 is a nuclear protein seen in proliferating cells but is absent in resting cells. Ki67 can be used as a prognostic marker for predicting the patient's survival. Hence, the current study aims to examine the expression of Ki-67 in oral and oropharyngeal squamous cell carcinomas. Objectives- 1. To estimate the prevalence of Ki67 expression in oral and oropharyngeal squamous cell carcinomas. 2. To correlate the expression of Ki67 in oral and oropharyngeal squamous cell carcinoma with histological grading.