Comparing the efficiency of ferrous Sulfate and ferrous ascorbate in Treatment of iron deficiency anemia in Children aged between 1-18 years of age Group – a randomized control trial

Abstract

INTRODUCTION: It is estimated that 42% of children aged < 5 years, 45-55% in children less than 12 years are anemic worldwide; the burden is even higher in India with 53.4% of children were found to be anemic in 2021, as per the NFHS-5. Over 30% of anemia is due to Iron deficiency. For the treatment of mild to moderate IDA, oral iron supplementation is employed. Conventionally, ferrous salts are advised, and several bivalent iron salts have been utilized as supplements. Ferrous sulfate, Ferrous Ascorbate are widely in use among them. Iron supplementation with oral formulations should be safe and well-tolerated. For good therapy compliance, iron preparation with favourable tolerability is therefore necessary. The objective of this study is effectiveness of both the salts in terms of their efficacy, tolerability and adverse events during the treatment . OBJECTIVES: Primary objective: To study the efficiency of oral iron preparations ferrous ascorbate, and ferrous sulfate in the treatment of iron deficiency anemia in children aged between 1-18 years of age group. Secondary objective: To study the effects of the salts. To study the effects of oral preparations.