Incidence and risk factors of Acute kidney injury in congenital Heart disease children post Cardiac surgery

Abstract

Background Understanding of the epidemiology of Acute kidney injury with the modifiable and non-modifiable risk factors, recognising the illness earlier, assessing the incidence and severity of acute kidney injury will prevent the adverse outcomes in the children undergoing cardiac surgery for their congenital heart diseases. The definition of paediatric AKI was standardized based on upgrading in serum creatinine levels or decreased in urine output . The introduction of Risk , injury , failure , loss , end stage kidney disease criteria & Modified version proposed by Acute Kidney Injury Network (AKIN) have increased the hypothetical of early prediction of AKI. Renal angina index (RAI), which is derived from variations in renal function, used to risk stratify critically ill children who are at high risk of AKI. It is believed that the Renal Angina Index may be used to identify early indicators of AKI. The RAI is an idea that seems appealing, but it hasn't been proven to work or validated in non-Western populations like Asian nations. Objectives: Primary objective : To compare AKIN criteria and Renal Angina Index (RAI) for early prediction of severe acute kidney injury in congenital heart disease patients undergoing cardiac surgery. SECONDARY OBJECTIVE : To ascertain the risk factors of acute kidney injury in these children.