Comparative evaluation of efficacy of Lignocaine HCL and Bupivacaine HCL used as a local drug delivery system for pain control after impacted mandibular third molar surgery: A single blinded randomized controlled trial

Abstract

ABTRACT BACKGROUND: Pain is a multifaceted sensation comprising both physiological and psychological reactions triggered by a harmful stimulus. It is a most common post operative sequalae associated with third molar surgery. This causes discomfort to patient and causes emotional and functional deficit. Non steroidal anti inflammatory drugs have been used to manage the post operative pain. NSAIDs have various complications and to eliminate that long acting anaesthetic drugs can be used alternatively. Lo cal drug delivery reduces systemic toxicity by sustained release of the drug to the target site. OBJECTIVE: To assess the efficacy of 2% Lignocaine HCL and 0.5% Bupivacaine HCL soaked in Absorbable gelatin sponge in reducing post operative pain associated with impacted mandibular third molar surgery.