Comparison of orthodontic resin adhesives incorporated with arginine and citrulline – an invitro study of physical, adhesive and antimicrobial properties

Abstract

ABSTRACT Introduction: The main goal of developing an adhesive that could bond the brackets directly to the tooth surface was to withstand forces from treatment and mastication while allowing complete control of biomechanical needs in orthodontics and prevention of damage to the enamel after removing these brackets. Further research in this aspect of orthodontics has led to achieving the goals of the adhesion of the bracket to the tooth surface. Arginine and Citrulline are semi-essential amino acids. These amino acids increase the cytoplasmic and environmental pH due to the synthesis of ammonia through the arginine deaminase pathway. This leads to an increase in the pH levels and synthesis of ATP. Thereby, there is maintenance of a neutral pH that is less beneficial for cariogenic activity. The purpose of this in vitro study is to evaluate and compare the effects of the addition of arginine, citrulline and a combination of Arginine and Citrulline to commercial orthodontic resin adhesive on the tensile strength, shear bond strength, and Antimicrobial Properties This study is focused on incorporating arginine and citrulline without unfavourably affecting the physical properties.