Comparative evaluation of the antimicrobial efficacy of anethum graveolens gel with chlorhexidine gel against aggregatibacter actinomycetemcomitans, porphyromonas gingivalis and fusobacterium nucleatum- an in vitro study

Abstract

ABSTRACT INTRODUCTION Periodontitis is an infection of the periodontium caused by group of specific microorganisms, resulting in progressive destruction of the periodontal ligament and alveolar bone with pocket formation. Therapeutic approaches which include mechanical scaling and root planing, is the first recommended periodontal therapy but it prevents sufficient reduction of the bacterial load due to lack of accessibility to microorganisms. Hence, incorporation of adjunctive chemotherapeutic agent enhances the outcome at sites not responsive to conventional therapy. Chlorhexidine is considered the gold standard for local drug delivery system but it has side effects like tooth staining, xerostomia and calculus formation. This has led to increasing in the demand for herbal medicine as they show fewer side effects and are cost effective. Among these herbal remedies is Anethum graveolens, which contains natural phytochemicals known for their therapeutic properties. AIM To compare and evaluate the antimicrobial efficacy of Anethum graveolens gel with Chlorhexidine gel against Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Fusobacterium nucleatum.