Estimation of salivary resistin Levels in individuals with healthy Periodontium and periodontitis

Abstract

ABSTRACT INTRODUCTION Research is currently underway to explore saliva as a noninvasive method for detecting biomarkers in the early monitoring of both oral and systemic diseases, with a specific emphasis on identifying the initial stages of periodontal tissue damage. Clinicians have long sought to establish connections between periodontal diseases and various systemic conditions by exploring different biological markers. Resistin has emerged as a significant marker which plays a vital role in various biological processes, especially inflammation. Initially recognized as an adipose-secreted hormone associated with obesity and insulin resistance in rodents, human resistin has been implicated in inflammation-related conditions, including periodontitis. Given its involvement in periodontal inflammation, resistin holds promise as a biomarker for identifying individuals at risk of developing periodontitis. Studies on resistin levels in periodontal health and disease have yielded inconclusive results. AIM Estimation of salivary Resistin levels in individuals with healthy periodontium and Periodontitis.