Comparative efficacy of mucoadhesive film containing silver nano particles and mucoadhesive film containing curcumin on wound healing after periodontal surgery – a randomized controlled trial

Abstract

INTRODUCTION The periodontium supports and preserves teeth, but periodontitis, which affects up to half of the global population, undermines these structures. Periodontal dressings (pack) are protective materials applied over the wound created by periodontal surgical procedures. The main objectives of periodontal dressings are to obtain an optimized healing and ensure minimum discomfort to the patient along with wound protection. While periodontal dressings aid in healing, they may also encourage bacterial growth. To address this, drug-loaded dressings including substances such as silver nanoparticles and curcumin have been investigated for antibacterial and anti-inflammatory activities. Given the potential of mucoadhesive films for targeted administration, this study assesses and compares the wound-healing efficacy of curcumin- and silver nanoparticle-based films after periodontal surgery. AIM To assess and juxtapose the impact of mucoadhesive films containing silver nano particles and mucoadhesive films containing curcumin on wound healing after periodontal surgery.