Quality Assesment Profiles of Selected Marketed Classical Ayurvedic Preparations by Chromatographic Techniques

Abstract

ABSTRACT This study presents a comprehensive investigation into churna formulations, employing a rigorous and systematic approach to evaluate their quality and composition. Through multifaceted analyses, including determination of foreign matter, powder microscopy, physicochemical characterization, microbial studies, physical powder characterization, organoleptic assessment, macroscopic studies, fluorescence studies, qualitative and quantitative phytochemical investigations and HPTLC analysis, a nuanced understanding of the formulations is achieved. Results indicate consistently low levels of foreign matter, highlighting meticulous quality control. Microscopic examination unveils distinct characteristics aiding in identification. Physicochemical parameters offer insights into solubility and acidity/alkalinity. Microbial studies ensure compliance with safety standards. Physical powder characterization reveals favorable flow properties. Organoleptic characterization indicates standardized sensory profiles. Macroscopic studies facilitate raw material identification. Fluorescence studies depict material behavior under different conditions. Qualitative phytochemical investigations enhance understanding of chemical composition, while quantitative assays provide analytical insight into key parameters. HPTLC analyses showcase method reliability, sensitivity, and eco-friendliness, with quantification of Piperine contributing to formulation characterization. The eco-friendliness evaluation emphasizes sustainable analytical practices. In conclusion, this study employs a holistic methodology to comprehensively characterize churna formulations, offering valuable insights into their quality, composition, and potential therapeutic efficacy, thus contributing to the advancement of herbal medicine