Comparison of budesonide spray And water based gel as an Endotracheal tube cuff lubricant On incidence of postoperative sore Throat: randomized control study

Abstract

Background: Postoperative sore throat (POST) is a common complication following endotracheal intubation under general anesthesia. Various pharmacological interventions, including corticosteroids and lubricants, have been explored to minimize its incidence. This randomized controlled study compares the effectiveness of budesonide spray and water-based gel (K-Y jelly) as endotracheal tube (ETT) cuff lubricants in reducing POST. Methods: A total of 178 patients, aged 18–60 years, undergoing elective surgery under general anesthesia were randomly assigned to two groups. Group B received 200 mcg of budesonide spray on the ETT cuff, while Group K had the cuff lubricated with 2 ml of K-Y jelly. The primary outcome was the incidence and severity of POST, assessed at multiple postoperative time points (immediately, 10 min, 1 hr, 6 hrs, and 24 hrs). Secondary outcomes included the incidence of postoperative cough and hoarseness.