To study the correlation of urine melatonin With metabolic syndrome and its Manifestation at tertiary care hospitala Cross sectional study

Abstract

Background: Metabolic Syndrome (MetS) is a cluster of conditions, including obesity, hypertension, dyslipidaemia, and hyperglycaemia, linked to cardiovascular diseases and type 2 diabetes. Melatonin, a hormone regulating sleep, has antioxidant and metabolic regulatory properties. Urinary melatonin levels are a non-invasive biomarker for melatonin production. This study explored the relationship between urinary melatonin levels and MetS in an Indian population with high MetS prevalence and limited melatonin research. Methods: A cross-sectional study was conducted at a tertiary care hospital in Belagavi, India (2023–2024). It included 120 MetS patients (NCEP ATP III criteria). Assessments included urinary melatonin, blood glucose, lipid profiles, blood pressure, and anthropometrics. Data were analyzed using SPSS and R software.