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http://localhost:8080/xmlui/handle/123456789/2106| Title: | Evaluate urine il -12p40 levels in Different stages of lupus nephritis –One-year cross-sectional study |
| Authors: | REG NO: BI0122001 |
| Keywords: | Systemic Lupus erythematosus, Lupus Nephritis, proteinuria, complement, Interleukin- 12 |
| Issue Date: | 2025 |
| Publisher: | KLE Academy of Higher Education and Research, Belagavi |
| Abstract: | Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disorder characterized by immune dysregulation and multi-organ involvement. Lupus nephritis (LN) is a severe complication of SLE, often requiring precise biomarkers for early detection and disease monitoring. IL- 12p40, a subunit of the pro-inflammatory cytokine IL-12, has emerged as a potential biomarker for LN, influencing Th1 immune responses and inflammation. Objective: ● To estimate IL-12 p40 level in urine among patients with lupus nephritis by ELISA to correlate the clinical presentation of SLE patients. ● To evaluate the association of variation of IL-12p40 levels with other biomarkers, in assessment of lupus nephritis. |
| URI: | http://localhost:8080/xmlui/handle/123456789/2106 |
| Appears in Collections: | Microbiology |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| BI0122001.pdf | 2.64 MB | Adobe PDF | View/Open |
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