Study of immunohistochemical expression of ki67 in prostate adenocarcinoma- a cross sectional hospital based study, Belagavi

Abstract

ABSTRACT TITLE: Study Of Immunohistochemical Expression Of Ki67 In Prostate Adenocarcinoma- A Cross Sectional Hospital Based Study, Belagavi. INTRODUCTION: Prostatic adenocarcinoma is one of the most common cancers worldwide and the cause of death of thousands of men every year. Gleason's scoring system is used to grade prostate cancer based on degree of glandular architecture and growth pattern of tumor. Ki67 is a classic cell proliferation marker that can be used to predict the aggressiveness of this cancer. Extent of mortality can be reduced by PSA screening in the elderly. OBJECTIVE: To study the correlation of Ki67 expression with PSA and histological grading of adenocarcinoma of prostate using Gleason's score and PSA levels.