Comparative evaluation of anti-candidal property of acrylic resin reinforced with magnesium oxide and silver nanoparticles and their effect on cytotoxic levels”: an in-vitro study

Abstract

STATEMENT OF PROBLEM: – Denture stomatitis is a common pathologic condition affecting 65% of denture wearers commonly associated with Candida species especially Candida albicans. Various measures like mechanical and chemical denture cleansing as well as use of local and systemic antibiotics have been tried to overcome this condition. Due to increase in resistance exhibited by the microorganisms to the existing treatment modalities, there is a need for development of polymethyl methacrylate (PMM) material having inherent activity especially against Candida albicans. Purpose: - To evaluate and compare the effect of the anti-candidal property of acrylic resin by incorporating silver nanoparticles and Magnesium oxide nanoparticles and also assessed its toxic cellular effects of different concentrations of nanoparticles on mice fibroblasts.