The Effect Of Preemptive Intravenous Paracetamol On Postoperative Analgesic Requirements In Patients Undergoing Laparoscopic Surgeries Under General Anaesthesia

Abstract

Background and Objectives ABSTRACT To determine the effect of preemptive use of 1g of IV paracetamol on postoperative pain scores and analgesic requirements in patients undergoing laparoscopic surgeries under general anaesthesia. Methods Sixty two American Society of Anesthesiologists physical status I and II patients undergoing laparoscopic surgeries were randomly divided into 2 equal groups. In the group I, 1g of IV paracetamol and in group II 100 ml normal saline IV was administered 30 min before induction over 15 min. Postoperative visual analog pain scores and requirement of tramadol were assessed. Results In this study significant high mean pain scores were observed at 15 min and 30 min during post operative period in group II ( 2.61±0.56 and 3.84±1.55 respectively ) compared to group I ( 2.06±0.63 and 2.35±1.17 respectively ) . ( P value 0.0006 and 0.0001 respectively ) . There was no significant difference in mean pain scores at one, two and six hours in both groups, which was due to administration of the rescue analgesic drug. ( p value ˃ 0.05) . The requirement for rescue tramadol analgesia was in 25.8% of patients in the group I compared to 64.5% of patients in group II. ( P<0.05) . IV Conclusion and interpretation To conclude, preemptive administration of 1g of IV paracetamol in patients undergoing laparoscopic surgeries provided good quality analgesia with decreased pain scores during the postoperative period, increased patient satisfaction and decreased postoperative tramadol consumption.