A Randomized Clinical Trail to Compare the Conditions for Laryngeal Mask Airway Insertion Following Induction with Sevoflurane and Propofol in Adults

Abstract

Background ABSTRACT Sevoflurane is a volatile anaesthetic agent, which combines rapid smooth inhalational induction of anaesthesia with rapid recovery, making ideal for day care anaesthesia. The laryngeal mask airway is often used in ambulatory anaesthesia, with intravenous propofol being the agent of choice for its insertion. Objective To compare conditions for LMA insertion following induction with propofol and sevoflurane viz, jaw opening, ease of insertion, patient responses and number of attempts for insertion of Laryngeal Mask Airway. Study design: A randomized double blind clinical trial. Methods After obtaining approval from the institutional ethical committee, 100 adults were allocated by computer generated randomization into two groups of 50 each; group P ( Propofol group) and group S ( Sevoflurane group ) . Patients in group P were induced with 2.5mg/kg intravenous Propofol and group S with 8% Sevoflurane in 50%O through inhalational route using the primed Bain’s circuit with vital capacity breath technique. After loss of eye lash reflex LMA was inserted after 1 minute and the grading of conditions for LMA insertion and number of attempts were noted. All the data collected was processed statistically. Results We observed excellent conditions for LMA insertion in group P ( 86% ) and in group S ( 84% ) with p value ( 0.786) which is statistically not significant. IX 2& N 2 O 50% Conclusion Sevoflurane compares favorably to i.v. Propofol for insertion of LMA using vital capacity inhalational technique.