Comparative Study Between L-Lysine and Regular Dressing in Chronic Foot Ulcers of Patients Admitted at KLES Dr. Prabhakar Kore Hospital and MRC, Belgaum

Abstract

Background and objectives The management of wound and wound dressing is an important aspect of chroniculcer management. Choosing an appropriate dressing can be a complex process. L-lysine is an amino acid which helps in faster wound remodelling. Objective The objective of the study was to assess the L-lysine dressings in comparison to conventional betadine dressings in achieving mean percentage wound reduction in patients with chronic foot ulcer of lower extremities more than four weeks duration, using transparency sheet. Methodology The present one year randomized controlled trial was conducted in the Department of Surgery, KLES Dr. PrabhakarKore Hospital and Medical Research Centre, Belgaum on 60 patients with infected diabetic foot ulcer during the period of January 2009 to December 2009. The patients were divided into two different groups by number randomization ( Group 1 L-lysine and Group 2 conventional betadine dressing) . Woundmeasurement was taken on day one and fourteen in both the groups. Percentage area of wound reduction was calculated. VII Results There was no statistical difference in the baseline characteristics like age, sex and initial wound area of the ulcer between the two groups. The percentage of area reduction was 32.30±7.00in patients treated with L-lysine dressings and 17.95±3.77in patients treated with betadine dressings, which is statistically significant ( p<0.001) . Conclusions limb. L-lysine dressing can be used for the healing of chronic foot ulcer of lower Key word