A Randomized Placebo Controlled Trial To Assess Post Operative Analgesia After Periportal Infiltration Of 0.75% Ropivacaine In Laparoscopic Appendicectomy

Abstract

Background and objectives ABSTRACT Although laparoscopic Appenicectomy is characterized by reduced postoperative pain, many patients still complain of moderate abdominal pain during the first 24 hours. The objective of this study was to compare effect of peri portal infiltration of 0.75% Ropivacaine versus saline for post-operative analgesia in laparoscopic Appendicectomy. Methodology 60 adult patients admitted to department of surgery posted for elective laparoscopic Appendicectomy in KLES Dr. Prabhakar Kore Hospital & MRC, Belgaum between age group 18 to 80 years of ASA-1 and ASA-2. 60 patients undergoing laparoscopic Appendicectomy were prospectively randomized into 2 groups. Group ( A ) – Study group: Patients received 20 ml 0.75% Ropivacaine periportally around all the three port sites at the start of surgery. Group ( B ) - Placebo group: Patients received 20 ml normal saline periportally at the same location. The evaluation of postoperative pain was done at fixed time interval according VAS. Analgesic requirements were analyzed. Results Mean pain scores upto 12 hours after surgery were lower in group ( A ) compared to group ( B ) . This difference was statistically significant ( p<0.05) . However, pain scores after 12 hours did not differ significantly between the two groups. The mean total NSAID’s usage in group( A ) was lower as compared to group ( B ) and was found to be statistically significant ( p<0.001 ) . V Conclusion To conclude, Ropivacaine is effective in preventing pain over the first 12h after laparoscopic Appendicectomy when preemptively given at the start of surgery.