Role Of C-Reactive Protein, Total Leucocyte Count, Neutrophil Percentage In Preoperative Diagnosis Of Acute Appendicitis” A Cross Sectional Study

Abstract

Background and Objectives A common blood analysis including white blood cell counts, neutrophil percentage and serum level of CRP has been demonstrated to be important in the diagnosis for acute appendicitis. The present study was aimed to find out the role of C-reactive protein, total leucocyte count and neutrophil percentage in preoperative diagnosis of acute appendicitis. Methodology This one year hospital based cross-sectional study was done on total of 160 patients admitted with clinical diagnosis of acute appendicitis at the Department of General Surgery, KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum from January 2012 to December 2012. Results In the present study 53.13% patients were females and the male to female ratio was 1:1.13. The commonest age of presentation was 21 to 30 years (38.75%) and the mean age was 27.60±8.43 years. All the patients presented with abdominal pain (100%) while RIF tenderness was commonest sign (100%). Based on HPR findings, 80.62% of patients were diagnosis as having acute appendicitis. HPR findings revealed 80.63% of patients with acute appendicitis. Conclusion and interpretation Raised CRP, TLC and direct count were seen in 75%, 63.75% and 66.75% of patients respectively. The sensitivity and specificity of CRP in predicting acute appendicitis was 96.12% and 90.32% respectively and total leukocyte count showed sensitivity and specificity of 96.90% and 90.32% respectively. The combined CRP, TLC and neutrophil percentage in predicting acute appendicitis showed sensitivity and specificity of 96.90% and 90.32% respectively.