Correlation of Hyperglycemia and Its Outcome In Patients With Acute Exacerbation Of Chronic Obstructive Pulmonary Disease – A Cross Sectional Study

Abstract

Background and Objectives ABSTRACT Chronic obstructive pulmonary disease ( COPD ) is a common, costly and preventable disease and is at present the fifth leading cause of death globally. The present study was undertaken to determine the relationship between blood glucose concentrations and clinical outcomes in patients admitted with AECOPD. Methods The present one year cross sectional study was conducted in Department of Internal and Respiratory Medicine, at KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum during January 2008 to December 2008 on 85 patients admitted with the diagnosis of AECOPD. Detailed history, clinical examination, blood investigations were performed. To establish the severity of exacerbation clinical questionnaire was used with gold classification alongwith arterial blood gas analysis and blood glucose measurements at the time of admission were noted. Results In this study majority of the patients were males ( 84.70% ) . Forty percent of the patients were in the age group of 61 to 70 years. All the patients ( n=85) complained of Dyspnea ( Grade 4 to Grade 5) . Out of the total 85 patients, 94% of male patients ( n=68) were smokers and 6% ( n=4) were nonsmokers. The smoking index in stage II patients was 230, in stage III it was 240 and in stage IV patients it was 270. The Median length of stay for all the patients in stage IV COPD was eight days. As the value of admission RBS increased so did the VIII median length of stay in the hospital ( p=0.002) . Median length of stay for all the patients in stage III was six days ( p=0.150 ) and in stage II patients it was five days ( p=0.6309) . The median length of stay of patients among the diabetic group was more than that of nondiabetic group ( 0.0002) . Conclusion The study can be concluded that higher the admission RBS, longer was the median duration of stay in the hospital for patients with severe COPD.