Correlation Of eGFR To Microvascular Complications In Type 2 Diabetes Patients” - A One Year Cross Sectional Study At KLES Dr.Prabhakar Kore Hospital & MRC Belgaum

Abstract

Background and objectives ABSTRACT Diabetes mellitus ( DM) is chronic disease which is reaching an epidemic proportion in many parts of the world. Estimated glomerular filtration rate ( eGFR ) estimation is probably the most rational noninvasive mode of assessing the renal status and the various Microvascular complications in Type 2 DM patients. The objective of the present study was to evaluate the correlation of estimated glomerular filtration rate ( eGFR ) to microvascular complications in type 2 diabetes mellitus patients. Methods The present prospective cross sectional study, was conducted in the Department of Medicine at KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum during the period of January 2008 to December 2008. The study was approved by the Ethical and Research Committee of J. N. Medical College, Belgaum. Fifty ( 50 ) Type 2 DM patients with duration of more than five years who fulfilled selection criteria were enrolled in the study and eGFR was measured. Results Results showed no significant difference in sex distribution among the study participants ( p=0.4876) . Subjects with declining eGFR had increased risk of microvascular complications like diabetic retinopathy, diabetic neuropathy and diabetic nephropathy ( p=0.0301) . Reduced eGFR was associated with hypertension in maximum number of cases ( p=0.0401) . IX Conclusion Reduced eGFR ( Glomerular Filtration Rate ) was significantly associated with various microvascular complications.