Study Of Serum Ferritin In Metabolic Syndrome And Its Components – A One Year Cross Sectional Study At Kle University, Belgaum

Abstract

Background and objectives ABSTRACT The metabolic syndrome is a cluster of risk factors for cardiovascular disease ( CVD ) , including obesity, hypertension, elevated triglycerides and low levels of HDL Cholesterol. Elevated serum ferritin levels have positive correlation between elevated ferritin levels. The present study was aimed to know the relationship between serum ferritin and metabolic syndrome and to evaluate its relationship with individual component of metabolic syndrome. Methodology The present study was conducted in the Department of Medicine, KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum during the study period from January 2011 to December 2011. Based on NCEP ATP III criteria, 100 cases with metabolic syndrome were enrolled. Serum ferritin was measured on fasting blood samples using radio-immunoassay. Results In this study, male preponderance was noticed. The most common age group was 51 to 60 years ( 30% ) and overall, the mean age was 55.84 ± 15.04 years. The commonest component of metabolic syndrome was hypertension 88%. Overall mean duration of hypertension was 9.68 ± 8.52 years and mean duration of diabetes was 9.52 ± 9.52 years. In this study lipid abnormalities revealed raised serum cholesterol, LDL, TG and low HDL among 61%, 15%, 86% and 81% respectively. Results of the present study showed serum ferritin was elevated significantly in individual components of metabolic syndrome ( Hypertension, V waist circumference, low HDL levels) though serum ferritin were elevated in patients of FBS and Triglyceride abnormality, but it was of statistically insignificant. Conclusion and interpretation Serum ferritin as a marker of metabolic syndrome was inconclusive but was raised significantly in individual components of metabolic syndrome.