A clinical profile of non motor Symptoms in parkinson’s disease” – a one Year cross sectional study

Abstract

Background and objectives ABSTRACT The nonmotor symptoms are universal features of idiopathic PD. They add significantly to the overall disability caused by PD and are the critical determinants of health related quality of life of affected patients. The present study was undertaken to assess the prevalence of prevalence of NMS in PD patients and to classify and analyse the NM symptoms on the basis of system involvement. Methodology The present study was undertaken to study the clinical profile of non motor symptoms in patients with PD, with the primary objective to know the prevalence of non motor symptoms in patients with PD and to classify and analyse the NMS on basis of systems involved. Results In the present study, prevalence of PD was more in the males compared to the females. The mean age of the study population was 57.92±9.03 and the mean duration of illness in our study was 2 years. Mean number of NMS among the study subjects was 13.2±3.55. The majority of the patients belonged to H and Y stage 3.0 and further, as the stage of the disease increased the mean number of non motor symptoms increased. Decreased libido was the most common autonomic symptom among PD patients. Among the gastro intestinal symptoms, unsatisfactory voiding of the bowel was the most common symptom accounting for 70% ( n=35) Dementia, anhedonia, and attention deficits were common IV neuropsychiatric symptoms with 62% ( n=31) each. Sensory symptoms of olfactory disturbances and unexplained pains were present in 64% ( n=32) and 82% ( n=41) patients respectively. Conclusion and interpretation The non motor symptoms were universally prevalent in all the patients with Parkinson’s disease. The number of non motors symptoms increased as the stage of the Parkinson’s disease progressed. Insomnia and unexplained pains were the most prevalent non motor symptoms.