A Study of Left Ventricular Dysfunction By Echocardiography in HIV Infected Patients - A One Year Cross Sectional Study at KLES Dr Prabhakar Kore Hospital, Belgaum

Abstract

Background and objectives ABSTRACT The advances in diagnosis, treatment, monitoring of HIV infection and the availability of antiretroviral drugs have lead to improved survival of patients but this has resulted in manifestations of late stage disease which includes cardiac involvement. This study was intended to find the association of Left Ventricular dysfunction in HIV infected patients. Methodology This one-year study was done from January 2016 to December 2016 in the Department of Medicine of a tertiary care hospital in North Karnataka. Prior to the commencement, ethical clearance was obtained. A total of 100 consecutive patients of HIV infection presenting to the medicine department were included. Patients were subjected to complete blood count. Electrocardiography and Echocardiography was performed on these patients to assess the cardiac involvement. Results Majority of the patients were males (76%) and the commonest age group involved was those between 40-49 years. In 73 patients (73%) duration of HIV infection was between 1 to 10 years. In this study, 79 patients (79%) were on treatment with Anti-Retroviral drugs. Cardiac manifestations were observed in 62% of the patients. Sinus tachycardia (29%) was found to be the most common cardiac manifestation on ECG. Diastolic dysfunction was present in 35 patients (35%) and systolic dysfunction was present in 49 patients (49%). V Conclusion and interpretation Patients with HIV infection are at higher risk of developing Left Ventricular dysfunction.